WCG新聞帖

[alexpon]

New Project: The Clean Energy Project

World Community Grid is pleased to announce its 11th new project: The Clean Energy Project. This project comes to you from researchers at Harvard University in Cambridge, Massachusetts, USA.

The mission of The Clean Energy Project is to find new materials for the next generation of solar cells and later, energy storage devices. By harnessing the immense power of World Community Grid, researchers can calculate the electronic properties of tens of thousands of organic materials - many more than could ever be tested in a lab - and determine which candidates are most promising for developing affordable solar energy technology.

Ultimately, with your support, scientists are expecting to create successful materials to produce efficient and inexpensive solar cells that will serve as viable solutions for our future energy needs.

For more information about The Clean Energy Project and other projects running on World Community Grid, please click here.

If you are currently contributing and want to check to see if you are contributing to this project, click here. If you are no longer contributing but would like to contribute to this project, please click here.


Technical Advisory: World Community Grid Moving Servers to a New Location

World Community Grid is getting brand new equipment and relocating its servers to a new IBM location. There is no action required on your part but we wanted you to be aware of the move.

The move starts on Wednesday, January 7, 2009 in the evening (approximately 0300 UCT January 8, 2009) and will require us to bring down the website for up to 48 hours.

During the downtime, your computer will be able to continue processing work units for your favorite World Community Grid research project. Your computer will know when the servers are back up and will then continue normal processing.

The move may cause your firewall to prompt you about World Community Grid. If this happens, please re-approve your computers access to World Community Grid.

For more information read this post in the member news forum.

We sincerely appreciate your wonderful support!

機器 Relocate 2天停機 自己屯WU囉

[alexpon]

http://www.worldcommunitygrid.org/proje ... paign=flu1 <--官網相關聯結
Influenza Antiviral Drug Search (抗流感藥物研究)

Project Status and Findings:
If you have comments or questions about this project, please visit the Influenza Antiviral Drug Search forum. For specific questions about the project, please go to the Influenza Antiviral Drug Search FAQs.

Mission
The mission of the Influenza Antiviral Drug Search project is to find new drugs that can stop the spread of an influenza infection in the body. The research will specifically address the influenza strains that have become drug resistant as well as new strains that are appearing. Identifying the chemical compounds that are the best candidates will accelerate the efforts to develop treatments that would be useful in managing seasonal influenza outbreaks, and future influenza epidemics and even pandemics.

Significance
Hundreds of thousands of people around the world die each year as a result of influenza infections. If a particularly virulent strain emerges that is readily transmitted among humans, a pandemic can potentially kill millions of people. The influenza virus mutates rapidly and therefore new varieties of influenza appear each year. Influenza vaccines are designed to anticipate the strains likely to be prevalent for the next flu season but can often miss newly evolved varieties. While drugs such as oseltamivir (commercial name Tamiflu) and zanamivir (commercial name Relenza) help keep influenza from spreading in the body, they do not work for all types of influenza and new drug resistant forms of influenza evolve and cannot be treated with these drugs. When drug resistant strains emerge, manufacturers designing vaccines may not be able to respond quickly enough to prevent a large outbreak of the disease. This project will search for promising new drug leads that stop the replication of the influenza viruses within the body, potentially helping patients who are not immune to a particular form of influenza. The discovery of both broad-spectrum and specific antiviral drugs is expected to significantly improve global health.

Approach
One promising approach to combat these viruses and prevent them from causing disease is to develop new drugs that inhibit neuraminidase (N1, N2, etc), NS1 protein, hemagglutinin, and possibly other targets that influenza needs to spread in the body. Using the known chemical structures of these target molecules, the project will perform virtual chemistry experiments and determine which of millions of known compounds attach to these target molecules in a manner that can disable or inhibit them, thus potentially keeping the influenza virus from spreading in the body. These experiments are performed using a program called AutoDock, from the Scripps Research Institute. This software is used for several other projects on World Community Grid. These include FightAIDS@Home, Discovering Dengue Drugs - Together, and Help Fight Childhood Cancer projects. Once drug candidates are identified using World Community Grid, then additional laboratory work, testing and ultimately drug trials will be required. This will likely not lead to any immediate treatments for influenza during the current H1N1 outbreak. However, influenza viruses cause recurrent seasonal disease outbreaks and have the potential for evolving into dangerous forms. Thus, proceeding on this project at this time will give us a better chance to be prepared for more serious outbreaks in the future.

又有新project 囉 加油

[Taiwan]

去年PCDVD曾號召F@H計畫裏台灣前三強團隊合組一個超強新團隊, 稱為Taiwan team, 有點類似SETI@Taiwan與SETI@Formosa合併一樣, 合併後好處顯而易見, 名次馬上往前排, 曝光率增加不少。

可是目前台灣尚沒有跨計畫整合的規劃, 我覺得很可惜, 以WCG計畫來看, 最強的團隊應是PCDVD@Taiwan, 好像有進入BOINC世界百大團隊排行之一, 而SETI計畫是SETI@Taiwan最強, 同樣都是BOINC平台, 如果可以合併, 不會影響團隊在各計畫裏的排名, 但合併後會提升在boinc團隊排名, 所以有利無弊, 惟一不同的是如果要跨計畫整合, 隊名都要改

[alexpon]

要有力人士吧 @@
Folding 滄者論壇大大 出力很多 還出卡 超有心.
幾大Project論壇頭頭可能也是需要找機會要喬一喬吧.
當然全都集中一團隊 分數是一定很精彩
台灣人都喜歡幾個人自己搞小團隊研發(中小企業來看)
也不是一定都不好 不過規模就是限制住了.
台灣民族性 是沒像內地那樣的 ~~怎說呢 不容易凝聚 (看政治就知了...離題了當我自我喃喃自語@@)
所以凝聚各project 高積分大大們的戰力 這些頭頭們要多參詳參詳怎個做法囉~~

[alexpon]

http://www.worldcommunitygrid.org/forum ... read=26618 <--來源
Discovering Dengue Drugs – Together (Phase 1) Completion
--------------------------------------------------------------------------------
World Community Grid is pleased to announce that as a result of the immense contribution of computing power from our members, Phase 1 of the Discovering Dengue Drugs – Together project finished on August 11, 2009.

The project launched on August 21, 2007 and ran for nearly 2 years. During that time over 159,000 members processed more than 25,500,000 results which required nearly 12,000 years of computing power from about 400,000 computers.

The project was interrupted for 17 weeks when Hurricane Ike made landfall in Galveston, Texas, USA, on September 17, 2008 and significantly damaged the research facility. Fortunately, none of the members of the research team and their families were injured and the facility was put back in working order. The project was re-started in late January, 2009.

A part of this project end, we also made some website updates. On the Research Pages and in the forums, the project is moved from Active Research to Completed Research.

Completing this project is a significant contribution to the research of Dengue Fever, Hepatitis C, West Nile, Yellow Fever and other diseases caused by the Flaviviridea family of viruses. This same research would have taken 205 years to complete on the computers that the researchers from UTMB had available to them in 2007.

Phase 1 was designed to serve as a comprehensive screening of approximately 3 million small "drug-like" molecules and identify several thousand molecules which attach to these virus enzymes in a manner that disables them. Molecules such as these may lead to drugs which can keep the disease from spreading in the body. The purpose of Phase 1 was to reduce the number of molecules being examined to only those that are the most promising candidates. These molecules will be further examined in Phase 2.

Phase 2 of the project will run each of the molecules identified in phase 1 through computationally demanding free energy calculations. The molecules that make it through this screening will be the candidates that show the most promising interactions with the virus enzymes and will be taken forward and further examined in the laboratory.

At this time, the researchers are busy performing post-processing on the results from Phase 1 and preparing for Phase 2. You may read about these plans and get the latest update from Dr. Stan Watowich in the following forum thread: http://www.worldcommunitygrid.org/forum ... read=26616.

On behalf of the Discovering Dengue Drugs - Together research staff at the University of Texas Medical Branch in Galveston, Texas, USA, we wish to express our thanks to you for contributing your computer power to this project. With your contribution, this phase of the project was completed in a fraction of the time it would otherwise have taken.

While we wait for Phase 2 to start, we still need your help with eight (8) other ongoing projects! World Community Grid continues to run the FightAIDS@Home, Help Conquer Cancer, Help Cure Muscular Dystrophy - Phase 2, Help Fight Childhood Cancer, Human Proteome Folding - Phase 2, Influenza Antiviral Drug Search, Nutritious Rice for the World, and The Clean Energy Project. All of these important projects need your computer time.

IMPORTANT: If you have elected to participate only in the Discovering Dengue Drugs - Together project, you must take some action to prevent your World Community Grid agent from sitting idle on your computer until the next phase of the project launches. Please sign in to World Community Grid, and from the "My Grid" page, select the "My Projects" link (http://www.worldcommunitygrid.org/ms/viewMyProjects.do) from the menu on the left. From the "My Projects" page, select one or more of the other projects in which you choose to participate or check the box labeled “If there is no work available for my computer for the projects I have selected above, please send me work from another project” and then press “save”.

第一階段完成 第二階段近期會展開

[alexpon]

Dear Contributor/Innovator,

Just wanted to let you know how your donated computer cycles are helping improve the planet.

FightAIDS@Home:
• Scripps Research Institute scientists recently found two compounds that will lead to new treatments for drug-resistant HIV strains
• The Grid is also being used to conduct virtual screening experiments to develop a new class of HIV inhibitors
Discovering Dengue Drugs - Together - Phase 2:
• The University of Texas Medical Branch has just launched an exciting project on the grid to identify promising drugs to combat Dengue and other related viruses
• Phase 2 of the project is designed to reduce the number of Phase 1 false positives (i.e., dead ends)
• As a result, Phase 2 will be much more productive, efficient, and rewarding
• Sign up to contribute to this project!
Here is more information about FightAIDS@Home, Discover Dengue Drugs - Together - Phase 2, or other projects running on World Community Grid.

Thanks again for donating your computer time to help with these terrific projects. Please let a friend know about the World Community Grid - we need all the computing power we can get to keep doing this important work.

The World Community Grid Team

If you wish to unsubscribe to this and all future emails from World Community Grid please click here.

[alexpon]

http://www.worldcommunitygrid.org/about ... n=rice_eop <--來源
13 Apr 2010

End of Nutritious Rice for the World project

Category: Nutritious Rice for the World
Tags: Project Event

Summary
World Community Grid is pleased to announce, that as a result of the generous contribution of computing power from our members, the Nutritious Rice for the World project finished on April 6, 2010.



Nutritious Rice for the World Research Project Completion

Member News

World Community Grid is pleased to announce that as a result of the generous contribution of computing power from our members, the Nutritious Rice for the World project finished on April 6, 2010.

The project was launched on May 12, 2008. While it was active, World Community Grid members processed over 29 million results which required nearly 26,000 years of computing power. This work would have taken about 200 years of time using the computing resources available to the researchers at the University of Washington. Using World Community Grid, this research was completed in less than two years.

With this project's completion, our members have significantly contributed to the research that is being done to ultimately develop rice strains that will make a difference in fighting malnutrition and feeding the world’s people.

Now comes the difficult part of sifting through the data to find the best models. The researchers need to find the best models from the almost 7 billion models generated. This should take approximately 3-6 months using their fastest methods. After identifying the most accurate models, they will use the information to figure out what functions these proteins perform in the rice organism. This involves comparing the structure and sequence to known proteins which is also a time consuming process. The plant genomes are not nearly as well studied as the human and mammalian genomes which makes the process all the more difficult.

You may read about these plans and get the latest update from The Nutritious Rice for the world scientists in this forum thread or on their website.

The Nutritious Rice for the World research staff at the University of Washington, USA wish to express their sincere gratitude to you for contributing your computer power to this project.

We still need your help with six (6) other ongoing projects! World Community Grid continues to run the following projects: FightAIDS@Home, Help Conquer Cancer, Help Cure Muscular Dystrophy - Phase 2, Help Fight Childhood Cancer, Human Proteome Folding - Phase 2, and Discovering Dengue Drugs – Together, Phase 2. All of these important projects need your computer time. If you only had Nutritious Rice for the World selected for active projects, then you will start receiving work from the other active projects. To modify your project selection criteria, please go to the My Projects Page.

大致就抗旱水稻計劃階段性完成,後續的將由人員整理資料了,一段時間(3-6個月)後等他們發表. 請各位繼續支持其它projet